gastroprotective effect of hydroalcoholic extract of aloe buettneri

نویسندگان

kossi metowogo centre de recherche et de formation sur les plantes médicinales, laboratoire de physiologie pharmacologie, faculté des sciences, université de lomé, bp: 1515 lomé, togo.

kwashie eklu-gadegbeku

amégnona agbonon

kodjo a. aklikokou

چکیده

aloe buettneri a. berger is commonly used in traditional togolese medicine to treat inflammatory and gastric ulcers. the present study examined the gastro-protection effect of the hydro-alcoholic extract of a. buettneri on mucus production and gastric ph. a gastric ulcer is induced by ethanol 95° alone (1 ml/kg body weight), after pre-treatment with indomethacin (300 mg/kg) or by utilising l-name (40 mg/kg iv). in addition gastric mucus was removed by scraping and subsequently weighed. the experiment focused entirely on rats that had been subjected to fasting. the hydro-alcoholic extract of a. buettneri (500 mg/kg) significantly inhibited ulcers that were induced by ethanol, indomethacin or l-name pre-treatment. a. buettneri was shown to increase the production of gastric mucus. furthermore l-arginine significantly decreased the size of the induced ulcers. the results achieved in the study carried out suggest that a. buettneri posses gastro-protective properties.

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منابع مشابه

Gastroprotective Effect of Hydroalcoholic Extract of Aloe buettneri

Aloe buettneri A. Berger is commonly used in traditional Togolese medicine to treat inflammatory and gastric ulcers. The present study examined the gastro-protection effect of the hydro-alcoholic extract of A. buettneri on mucus production and gastric pH. A gastric ulcer is induced by ethanol 95° alone (1 mL/kg body weight), after pre-treatment with indomethacin (300 mg/kg) or by utilising L-NA...

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Gastroprotective Effect of Hydroalcoholic Extract of Aloe buettneri

Aloe buettneri A. Berger is commonly used in traditional Togolese medicine to treat inflammatory and gastric ulcers. The present study examined the gastro-protection effect of the hydro-alcoholic extract of A. buettneri on mucus production and gastric pH. A gastric ulcer is induced by ethanol 95° alone (1 ml/kg body weight), after pre-treatment with indomethacin (300 mg/kg) or by utilising L-NA...

متن کامل

Gastroprotective Effect of Hydroalcoholic Extract of Aloe buettneri

Aloe buettneri A. Berger is commonly used in traditional Togolese medicine to treat inflammatory and gastric ulcers. The present study examined the gastro-protection effect of the hydro-alcoholic extract of A. buettneri on mucus production and gastric pH. A gastric ulcer is induced by ethanol 95° alone (1 ml/kg body weight), after pre-treatment with indomethacin (300 mg/kg) or by utilising L-NA...

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Gastroprotective Effect of Hydroalcoholic Leaves Extract of Pongamia Pinnata

Pongamia pinnata has long been used in folk medicine in treatment for bronchitis, whooping cough, rheumatic arthritis, and diabetes, various inflammatory conditions and dyspepsia. Therefore, Present study was designed to investigate the antiulcer effect of hydroalcoholic extract of leaves of P. pinnata (HLEPP) using different models of gastric ulceration in rats. Hydroalcoholic extract of leave...

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Anti-ulcer and Anti-inflammatory Effects of Hydro- alcohol Extract of Aloe buettneri A. Berger (Lilliaceae)

Purpose: Aloe buettneri A. Berger is commonly used in Togolese folk medicine to treat inflammation and gastric ulcer. In this study we investigated the anti-oedema, analgesic, antipyretic and ulcer healing properties of the hydro-alcohol extract of their leaves. Methods: Rat oedema paw were induced by the injection of 0.1 ml of formaldehyde 1%, tail flick method is used to study analgesic prope...

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عنوان ژورنال:
iranian journal of pharmaceutical research

جلد ۲۰۱۱، شماره ۳، صفحات ۶۹-۷۴

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